Marcus Stroman was born and raised in Medford, NY where he attended Patchogue-Medford High School.  He was drafted out of high school in the 18th round (532nd overall) of the 2009 Major League Baseball Draft by the Washington Nationals, but did not sign and chose to attend Duke University.  At Duke, Stroman compiled a career record of 15-13 in 48 appearances and still holds the record for career strikeouts (290 over 222 IP).  Stroman also made 97 appearances as a position player for the Blue Devils, mostly at second base and shortstop.

Stroman was drafted in the 1st round (22nd overall) in the 2012 Major League Baseball Draft by the Toronto Blue Jays and became the first Duke player ever selected in the first round.  He made his Major League debut on May 6, 2014 and made his first Major League start on May 31, 2014, pitching six innings and surrendered only one earned run on five hits, striking out six and issuing no walks to earn the win over the Kansas City Royals.

On March 10, 2015 he suffered a tear to the ACL in his left knee, leaving many to assume he would miss the 2015 season.  Devastated by the setback but more determined than ever, Stroman used this injury and his rehabilitation to motivate himself to join his teammates in the post-season.  Always looking for ways to better himself, Marcus used this time to return to Duke to rehabilitate his knee while finishing up his degree.  Stroman made his 2015 debut on September 12 against the New York Yankees, pitching five innings and earning the win.  He finished the 2015 regular season with a 4-0 record, 1.67 ERA, and 18 strikeouts on 27 innings pitched.

On March 23, 2016, Stroman was named the Opening Day starter for the Blue Jays.